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Updated: Mar 22, 2026

CO2-Lasertonsillotomy Under Local Anesthesia in Adults

CO2-Lasertonsillotomy Under Local Anesthesia in Adults

Published on: November 6, 2019

[Tonsillectomy for PANDAS?].

¹Klinik für HNO-Krankheiten, Plastische Kopf- und Hals-Chirurgie, Allergologie, Kliniken Maria Hilf, Mönchengladbach.

Laryngo- Rhino- Otologie

|April 30, 2016

Summary

This summary is machine-generated.

Tonsillectomy (TE) may not effectively treat Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS). Case reports showed positive outcomes, but larger studies did not support these findings, suggesting caution in its use.

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Published on: October 13, 2017

Area of Science:

Otolaryngology
Pediatric Neurology
Psychiatry

Background:

Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) links streptococcal infections to OCD and tic disorders in children.
Tonsillectomy (TE) is often considered for PANDAS due to recurrent streptococcal infections.

Purpose of the Study:

To evaluate the efficacy of tonsillectomy (TE) in pediatric patients with a verified diagnosis of PANDAS.

Main Methods:

A systematic PubMed search was conducted for studies published between January 1, 1995, and July 31, 2015.
Search terms included "tonsillectomy" and "PANDAS", "OCD", "compulsive", "pediatric autoimmune", "Chorea", and "Tic".
Reviews without patient data were excluded.

Main Results:

Nine papers were identified: 6 case reports (8 patients) and 3 case series.
Case reports suggested TE was beneficial, but case series findings did not support this.
Follow-up periods ranged from 2-36 months for case reports and 24-36 months for case series.

Conclusions:

Diagnosing PANDAS is challenging due to comorbidities and lack of biomarkers.
Reported positive outcomes after TE may be confounded by postoperative medication.
Given potential morbidity and mortality, TE for PANDAS should be limited to clinical studies with standardized criteria.