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Coronary Artery Ectasia-A Review of Current Literature

Subodh Devabhaktuni1, Ana Mercedes, Jimmy Diep

  • 11701 W Charleston Blvd., Suite: 230, Las Vegas, NV-89102, USA. sdevabhaktuni@unr.edu.

Current Cardiology Reviews
|May 5, 2016
PubMed

Insights

Coronary artery ectasia (CAE) is an uncommon cardiovascular condition, often linked to atherosclerosis. Current management strategies for CAE remain under discussion despite its long history.

Area of Science:

  • Cardiology
  • Vascular Biology

Background:

  • Coronary artery ectasia (CAE) is a rare cardiovascular disorder with an incidence of 1.2%-4.9%.
  • It is characterized by excessive expansive vascular remodeling, primarily caused by atherosclerosis.
  • Despite being known for over 50 years, its optimal management is still debated.

Purpose of the Study:

  • To review the existing literature on coronary artery ectasia.
  • To consolidate information on the pathophysiology, diagnosis, and management of CAE.

Main Methods:

  • A comprehensive literature search was conducted using PubMed and Google Scholar.
  • Keywords included "coronary artery ectasia", "coronary artery aneurysm", "pathophysiology", "diagnosis", and "management".
  • Full articles and review articles were analyzed, focusing on pathophysiology, diagnosis, and management.

Main Results:

  • Coronary artery ectasia is strongly associated with atherosclerosis, representing an exaggerated remodeling response.
  • The review synthesized current knowledge regarding the underlying mechanisms, diagnostic approaches, and therapeutic options for CAE.
  • Atherosclerosis is identified as the predominant cause of CAE.

Conclusions:

  • Coronary artery ectasia, while uncommon, necessitates further research into standardized diagnostic and management protocols.
  • Understanding the pathophysiology is crucial for developing effective treatments.
  • The ongoing debate highlights the need for evidence-based guidelines for CAE.

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