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Auditory Brainstem Response Improvements in Hyperbillirubinemic Infants
Farzaneh Zamiri Abdollahi1, Tayebeh Ahmadi1, Vinaya Manchaiah2
1Department of Audiology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Journal of Audiology & Otology
|May 5, 2016
Summary
High bilirubin levels in infants can cause temporary auditory nerve damage. Auditory neuropathy in hyperbilirubinemic infants showed significant improvement three months after treatment, suggesting reversibility.
Area of Science:
- Neonatal Medicine
- Auditory Neuroscience
- Pediatric Neurology
Background:
- Hyperbilirubinemia in infants is linked to potential neuronal damage, including the auditory system.
- Some evidence suggests that bilirubin-induced auditory damage might be temporary and reversible.
Purpose of the Study:
- To investigate auditory neuropathy in infants with hyperbilirubinemia.
- To assess the reversibility of auditory abnormalities following hyperbilirubinemia treatment.
Main Methods:
- Included 41 hyperbilirubinemic infants and 39 controls.
- Hearing evaluations (transient evoked otoacoustic emission and auditory brainstem response) were performed twice: post-treatment and three months later.
- Auditory Brainstem Response (ABR) and Transient Evoked Otoacoustic Emission (TEOAE) were used.
Main Results:
- Transient Evoked Otoacoustic Emission (TEOAE) results did not significantly change in either group.
- Auditory Brainstem Response (ABR) results in the hyperbilirubinemic group showed significant improvement from the first to the second assessment (p=0.025).
- Control group TEOAE and ABR results remained stable.
Conclusions:
- Bilirubin-induced auditory neuronal damage appears to be reversible over time.
- Infants with hyperbilirubinemia who do not pass initial hearing tests should be reevaluated after three months.
