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Related Concept Videos

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Related Experiment Video

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Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis
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Preclinical Multimodality Imaging in Vivo.

David B Stout1, Habib Zaidi2

  • 1Crump Institute for Molecular Imaging, Department of Molecular and Medical Pharmacology, The David Geffen School of Medicine at UCLA, 570 Westwood Plaza, CNSI Building, Room 2151, Los Angeles, CA 90095, USA.

PET Clinics
|May 10, 2016
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Summary

Multimodality small-animal imaging is crucial for studying human disease models in rodents. High-resolution techniques offer complementary data for advanced biomedical research.

Keywords:
Biomedical researchImage fusionMolecular imagingMultimodality imagingSmall-animals

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Area of Science:

  • Biomedical research
  • Preclinical imaging
  • Molecular imaging

Background:

  • Transgenic and knockout rodent models are vital for studying human diseases.
  • High-resolution multimodality molecular imaging is increasingly necessary for these models.

Purpose of the Study:

  • Discuss current trends in preclinical multimodality imaging.
  • Explore new horizons in in-vivo imaging techniques.
  • Highlight the role of multimodality imaging in biomedical research.

Main Methods:

  • Combining imaging modalities for sequential or simultaneous data acquisition.
  • Utilizing high spatial resolution and sensitivity instrumentation.
  • Focusing on in-vivo preclinical imaging applications.

Main Results:

  • Multimodality imaging provides complementary information.
  • High-resolution techniques enhance data quality in rodent models.
  • Imaging advances support disease modeling and research.

Conclusions:

  • Preclinical multimodality imaging is essential for modern biomedical research.
  • Technological advancements offer new possibilities for in-vivo studies.
  • This field plays a critical role in understanding human diseases through animal models.