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Updated: Mar 21, 2026

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Published on: September 5, 2017
Fever of Unknown Origin: The Roles of FDG PET or PET/CT
Jigang Yang1, Hongming Zhuang2, Sabah Servaes3
1Department of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, 95 Yong An Road, Xi Cheng District, Beijing 100050, China; Department of Radiology, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA.
Abstract:
Despite advances in medicine in the past decades, fever of unknown origin (FUO) remains a challenging and common clinical problem. There are many different etiologies for FUO. Positron emission tomography/computed tomography (PET/CT) is a powerful technique that has been proven to be useful in elucidating processes that may present as FUO. This article reviews the utility of PET/CT imaging in the evaluation of FUO, with attention to the pediatric population.
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