A saccharide-based crystalline sponge for hydrophilic guests
Guo-Hong Ning1, Kazuki Matsumura1, Yasuhide Inokuma1
1Department of Applied Chemistry, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan. inokuma@appchem.t.u-tokyo.ac.jp mfujita@appchem.t.u-tokyo.ac.jp.
Chemical Communications (Cambridge, England)
|May 10, 2016
Summary
Researchers developed a
Area of Science:
- Supramolecular Chemistry
- Crystallography
- Organic Chemistry
Background:
- Crystalline sponge methodology enables the analysis of hydrophilic compounds.
- Designing porous materials with specific guest-binding properties is challenging.
Purpose of the Study:
- To synthesize a novel coordination network for crystalline sponge analysis.
- To demonstrate the utility of this 'sugar sponge' for analyzing hydrophilic guest structures.
Main Methods:
- Synthesis of a mannose-based organic ligand and sodium ion coordination network.
- Crystalline sponge analysis utilizing the synthesized material.
- Structure determination of trapped hydrophilic guest molecules.
Main Results:
- A 'sugar sponge' coordination network was successfully synthesized.
- The network effectively trapped hydrophilic guest molecules via hydrogen bonding.
- The 'sugar sponge' was used to determine the structures of flexible alcohols and the absolute configurations of chiral epoxides.
Conclusions:
- The mannose-based 'sugar sponge' is a viable tool for crystalline sponge analysis.
- This method allows for the structural elucidation of challenging hydrophilic compounds.
- The 'sugar sponge' offers a new approach for analyzing molecular configurations.
