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Development of the Limb Synovial Joints01:07

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Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
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Structural Joints: Synovial Joints01:16

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Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
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Knee Joint01:23

Knee Joint

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The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
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Bone Disorders01:29

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
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Glycosaminoglycans (GAGs), also known as mucopolysaccharides, are long and linear polymers comprising of specific repeating disaccharides - the amino sugar that can be N-acetylglucosamine or N-acetylgalactosamine, and a uronic acid that is usually glucuronic acid or iduronic acid.
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Synovial Fluid Analysis to Identify Osteoarthritis
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Synovial osteolipoma.

Radha Sistla1, Josyula Venkata Satya2, Tameem Afroz1

  • 1Department of Anatomical Pathology, Cytology, Global Hospitals, Hyderabad, Telangana, India.

Indian Journal of Pathology & Microbiology
|May 12, 2016
PubMed
Summary
This summary is machine-generated.

Intraarticular synovial osteolipoma, a rare tumor containing bone, is exceptionally uncommon. This report details a significantly large 12 cm × 10 cm knee osteolipoma, exceeding previously documented sizes.

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Area of Science:

  • Orthopedic Oncology
  • Skeletal Pathology
  • Tumor Histology

Background:

  • Intraarticular synovial osteolipoma is a rare tumor characterized by mature lamellar bone within lipomatous tissue.
  • Previous literature documents only two cases of this rare entity.
  • The largest reported joint osteolipoma measured 3 cm × 4 cm.

Observation:

  • This study presents an exceptionally large intraarticular synovial osteolipoma in the knee.
  • The tumor measured 12 cm × 10 cm, significantly larger than previously reported cases.
  • The knee is identified as a common anatomical site for this tumor.

Findings:

  • The case highlights a substantial osteolipoma within the knee joint.
  • The tumor's size is unprecedented in the existing medical literature.
  • Histological confirmation of mature lamellar bone within the lipoma is key.

Implications:

  • This finding expands the known size spectrum for intraarticular synovial osteolipomas.
  • It underscores the importance of considering rare differential diagnoses in large joint masses.
  • Further research may be warranted to understand the growth potential and behavior of these large tumors.