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Updated: Mar 21, 2026

Platelet-Rich Plasma Lysate for Treatment of Eye Surface Diseases

Platelet-Rich Plasma Lysate for Treatment of Eye Surface Diseases

Published on: August 2, 2022

Solid Platelet Rich Plasma in Corneal Surgery.

Francisco Arnalich¹, Alejandra E Rodriguez², Alvaro Luque-Rio²

¹Department of Cornea and Refractive Surgery, VISSUM, Madrid, Spain.

Ophthalmology and Therapy

|May 16, 2016

Summary

This summary is machine-generated.

Solid eye platelet-rich plasma (E-PRP) effectively promotes corneal wound healing in severe ulcers and perforations. This surgical coadjuvant offers a reliable alternative for ocular surface reconstruction, enhancing physiological healing processes.

Keywords:

Amniotic membrane Corneal surgery Fibrin membrane PRP Platelet-rich plasma Tutopatch

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Area of Science:

Ophthalmology
Regenerative Medicine
Biomaterials

Background:

Platelet-rich plasma (PRP) concentrates growth factors crucial for healing.
Solid E-PRP is a novel formulation for ophthalmic applications.
Alternative biomaterials like bovine pericardium and fibrin membranes exist but have limitations.

Purpose of the Study:

To evaluate the efficacy of solid eye platelet-rich plasma (E-PRP) as a surgical coadjuvant.
To assess E-PRP's role in promoting corneal wound healing.
To compare E-PRP with other biomaterials for ocular surface reconstruction.

Main Methods:

Concentration of platelets and growth factors in E-PRP.
Application of E-PRP in cases of severe corneal ulcers and perforations.
Association of E-PRP with other ocular surface reconstruction procedures.

Main Results:

E-PRP demonstrated reliability and effectiveness in promoting corneal wound healing.
E-PRP enhances physiological healing at injury sites.
E-PRP offers advantages over amniotic membrane patches, including reduced variability and biological hazards.

Conclusions:

Solid E-PRP is a reliable and effective surgical coadjuvant for corneal wound healing.
E-PRP is beneficial for severe corneal ulcers and perforations.
E-PRP can be integrated into various ocular surface reconstruction procedures.