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The unexpected truth about dates and hypoglycemia.

Mohammed I Yasawy1

  • 1Department of Internal Medicine, College of Medicine and King Fahd Hospital of the University, University of Dammam, Dammam, Kingdom of Saudi Arabia.

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|May 18, 2016
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Summary

Hereditary fructose intolerance (HFI) can cause hypoglycemia after eating dates. Early diagnosis through fructose intolerance testing and dietary changes can prevent severe health issues.

Keywords:
Datesheredity fructose intolerancehypoglycemia

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Area of Science:

  • Metabolic Disorders
  • Gastroenterology
  • Nutritional Science

Background:

  • Dates are nutrient-dense, providing carbohydrates like glucose and fructose, commonly consumed in Saudi Arabia.
  • Hereditary fructose intolerance (HFI) is a rare condition where fructose ingestion can lead to hypoglycemia.
  • This study investigates preliminary findings in patients experiencing hypoglycemia after consuming dates.

Purpose of the Study:

  • To report on patients with undiagnosed hypoglycemia linked to date consumption.
  • To highlight the potential for HFI to manifest later in life.
  • To emphasize the importance of accurate diagnosis and dietary management for HFI.

Main Methods:

  • Case report involving three patients from the same family in Saudi Arabia.
  • Clinical evaluation including detailed dietary history and laboratory investigations.
  • Diagnosis confirmed by a fructose intolerance test (FIT).

Main Results:

  • Patients presented with symptoms like bloating, nausea, hypoglycemia, sleepiness, sweating, and shivering after eating dates.
  • FIT confirmed hereditary fructose intolerance (HFI) in all three patients.
  • A fructose-free diet led to complete symptom resolution.

Conclusions:

  • HFI can remain undiagnosed into adulthood, potentially leading to severe complications.
  • Suspecting HFI based on dietary history and confirming with FIT is crucial for diagnosis.
  • Dietary restriction of fructose is an effective management strategy for HFI patients.