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Current Developments on Optical Feedback Interferometry as an All-Optical Sensor for Biomedical Applications.

Julien Perchoux1, Adam Quotb2, Reza Atashkhooei3

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This summary is machine-generated.

Optical feedback interferometry (OFI) sensors offer contactless, low-cost biosensing. This review highlights OFI

Keywords:
biophotonicsbiosensorsflowmetrymetrologyoptical feedback interferometryvibrometry

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Area of Science:

  • Biophotonics and Biosensing
  • Optical Measurement Techniques

Background:

  • Optical feedback interferometry (OFI) sensors are increasingly adopted in biosensing.
  • Their contactless nature, low cost, and compactness align with biophotonics trends.

Purpose of the Study:

  • To review ongoing work applying OFI to diverse in vivo and ex vivo biosensing applications.
  • To showcase the breadth of opportunities and potential applications of OFI in biosensing.

Main Methods:

  • Two primary sensing strategies are explored: optical path change measurement and flow monitoring.
  • Optical path changes involve amplitude reconstruction from interferometric signals.
  • Flow monitoring utilizes classical Doppler frequency measurements.

Main Results:

  • Optical path change measurements demonstrated utility for transient pulse detection and large displacement sensing in palliative care for Parkinson's disease.
  • Doppler-based approaches showed progress in flow-related signal processing for real-time monitoring of non-steady flows, human blood flow, and OFI pressure myography.
  • Experimental results across various setups confirm the versatility and high accuracy of OFI sensors.

Conclusions:

  • OFI sensors exhibit wide-ranging capabilities in biosensing.
  • They serve as enablers for low-cost, all-optical, high-accuracy biomedical applications.
  • The technique's versatility supports diverse biosensing needs.