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[New Possibilities in Retinal Diagnostics Using OCT Angiography].

G E Lang1, C Enders1, J U Werner1

  • 1Augenklinik, Universitätsklinikum Ulm.

Klinische Monatsblatter Fur Augenheilkunde
|May 18, 2016
PubMed
Summary
This summary is machine-generated.

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Optical coherence tomography angiography (OCTA) offers detailed 3D imaging for diagnosing posterior eye diseases like diabetic retinopathy and AMD. While it complements fluorescein angiography, its limited field of view requires further study for widespread replacement.

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Retinal Diagnostics

Background:

  • Optical coherence tomography angiography (OCTA) instruments are now available for clinical use.
  • This paper evaluates OCTA's capabilities, benefits, and drawbacks in diagnosing posterior eye segment diseases.

Purpose of the Study:

  • To assess the clinical utility of OCTA in diagnosing common posterior segment eye conditions.
  • To compare OCTA findings with traditional fluorescein angiography (FA).

Main Methods:

  • Patients with diabetic retinopathy, retinal vascular occlusions, and age-related macular degeneration were included.
  • OCTA (AngioPlex™) imaging was performed, with optional 3x3mm scans for regions of interest.
  • OCTA findings were correlated and compared with fluorescein angiography (FA) results.

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Main Results:

  • OCTA provided rapid, non-invasive, 3D visualization of retinal and choroidal microvasculature.
  • It reliably detected microaneurysms, IRMA, non-perfusion, FAZ changes, and neovascularization.
  • OCTA offered superior spatial detail compared to FA, though its peripheral field is limited; macular edema diagnosis is aided by OCT thickness measurements.

Conclusions:

  • OCTA is a valuable, non-invasive diagnostic tool providing crucial 3D vascular information for posterior eye diseases.
  • Its speed and ease of use make it suitable for monitoring and potentially early diagnosis.
  • Further prospective studies are needed to define OCTA's role and its potential to replace FA in specific retinal and choroidal disease diagnostics.