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Blue Cell Tumour at Unusual Site: Retropritoneal Ewings Sarcoma
Anita P Javalgi1, Mahesh H Karigoudar2, Katyayani Palur3
1Assistant Professor, Department of Pathology, Shri B M Patil Medical College , Sholapur Road Bijapur, Karnataka, India .
Journal of Clinical and Diagnostic Research : JCDR
|May 19, 2016
Summary
A rare retroperitoneal Ewing's sarcoma was diagnosed in a 39-year-old female. Accurate diagnosis through immunohistochemistry confirmed extraskeletal Ewing's sarcoma, aiding management and improving survival.
Area of Science:
- Oncology
- Pathology
Background:
- Ewing's sarcoma is a rare, highly malignant tumor with osseous or non-osseous origin.
- Extraskeletal Ewing's sarcoma can arise from soft tissues, often presenting in the retroperitoneum.
Observation:
- A 39-year-old female presented with abdominal discomfort, vague pain, lower limb weakness, and weight loss.
- MRI revealed a 10x10 cm retroperitoneal mass; laparotomy was performed due to suspicion of uterine sarcoma.
- The mass was found to be adherent to the posterior uterus.
Findings:
- Histopathological examination suggested a blue cell tumor with PAS positivity.
- Immunohistochemistry confirmed extraskeletal Ewing's sarcoma/primitive neuroectodermal tumor, positive for S100, Vimentin, and CD99.
- The tumor was negative for desmin and cytokeratin.
Implications:
- Accurate diagnosis of retroperitoneal Ewing's sarcoma is crucial for effective patient management.
- Timely diagnosis and targeted therapy can significantly improve survival rates for this rare malignancy.
