Effect of temperature on fixation suppression ability in normal subjects: the need for temperature- and age-dependent...

The purpose of the present investigation was to determine whether temperature has an effect on the magnitude of fixation suppression (FS) in normal subjects. The subject population consisted of 23 patients ranging in age from 35 to 74 years (mean age of 58.13 years). Each subject received a conventional vestibulometric test battery that included bithermal caloric testing and the FS test. The warm caloric media elicited larger nystagmus slow-phase eye velocities than the cool caloric media. Following warm caloric irrigations, FS was significantly smaller than that following cool caloric irrigations. It also worsened as a function of subject age. The results suggest that separate normal upper limits for FS need to be determined for cool and warm caloric testing. They also suggest that FS ability may decrease with age.