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Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Imaging Studies VII: Vascular Imaging01:19

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DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
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Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
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Imaging Biological Samples with Optical Microscopy01:18

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Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Voxel Based Morphometry in Optical Coherence Tomography: Validation & Core Findings.

Bhavna J Antony1, Min Chen2, Aaron Carass1

  • 1Department of Electrical and Computer Engineering, Johns Hopkins University.

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|May 21, 2016
PubMed
Summary
This summary is machine-generated.

This study validates voxel-based morphometry (VBM) for retinal Optical Coherence Tomography (OCT) analysis. VBM reveals retinal changes in multiple sclerosis (MS) patients, offering new insights into this subtype.

Keywords:
RAVENSmultiple sclerosisnormalized atlasoptical coherence tomographyregistrationretinavoxel-based morphometry

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Area of Science:

  • Ophthalmology
  • Neuroimaging
  • Medical Imaging Analysis

Background:

  • Optical coherence tomography (OCT) is crucial for diagnosing ocular diseases.
  • Voxel-based morphometry (VBM) is a neuroimaging technique for regional brain analysis.
  • Registration methods for OCT are underdeveloped, limiting VBM applications in population studies.

Purpose of the Study:

  • To explore the benefits of VBM analysis for OCT data.
  • To validate VBM stability in healthy control cohorts.
  • To investigate retinal changes in multiple sclerosis (MS) patients using VBM.

Main Methods:

  • Developed and applied a novel OCT registration method.
  • Validated VBM analysis stability across two healthy control cohorts.
  • Conducted a retrospective study comparing age/sex-matched healthy controls and relapsing-remitting MS patients.

Main Results:

  • VBM analysis demonstrated stability in healthy controls.
  • Retinal changes associated with relapsing-remitting MS were identified.
  • Results align with existing literature on MS-related retinal alterations.

Conclusions:

  • VBM is a stable and valuable analysis technique for retinal OCT data.
  • This approach provides insights into the specific retinal changes in MS subtypes.
  • Further application of VBM in OCT-based population studies is warranted.