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Published on: June 20, 2018
[Polypous rhinosinusitis in the children]
E P Karpova1, M P Emel'yanova1, D A Tulupov1
1Russian Medical Academy of Post-Graduate Education, Moscow, Russia, 125993.
Insights
Polypous rhinosinusitis (PRS) in children is often linked to allergies and cystic fibrosis. Mometasone furoate nasal spray shows promise for treating pediatric PRS, though more research is needed.
Area of Science:
- Otolaryngology
- Pediatric Allergy and Immunology
- Rhinology
Context:
- Polypous rhinosinusitis (PRS) is a chronic sinonasal inflammatory condition.
- Understanding PRS in children requires comparison with adult presentations.
- Key associated conditions include allergic diseases and cystic fibrosis.
Purpose:
- To review current literature on pediatric polypous rhinosinusitis (PRS).
- To compare PRS in children with that in adult patients.
- To identify potential therapeutic strategies for pediatric PRS.
Summary:
- Allergic diseases and cystic fibrosis are primary risk factors for nasal polyps in children.
- Unlike adults, pediatric PRS rarely involves disorders of arachnoid acid metabolism.
- Intranasal glucocorticosteroids, particularly mometasone furoate nasal spray, are a promising treatment for pediatric PRS.
Impact:
- Highlights the distinct etiological factors of PRS in pediatric versus adult populations.
- Identifies intranasal glucocorticosteroids as a potential primary treatment for pediatric PRS.
- Emphasizes the need for further clinical trials to validate the efficacy and safety of treatments for pediatric PRS.
Abstract:
We present an overview of the modern literature concerningpolypous rhinosinusitis (PRS) in the children. The information thus derived is compared with the available results of the clinical investigations involving the adults patients with this pathology. Allergic diseases and mucoviscidosis appear to be the pathological conditions most likely leading to the development of polyps in the nasal cavity. The patients suffering from rhinosinusitis associated with the disorders of arachidonic acid metabolismare very rarely encountered in the pediatric practice unlike those among the adult population. Intranasal glucocorticosteroids (INGCS), especially in the form of the mometasonefuroate nasal spray, are considered to be the most promising medications for the treatment of the children presenting with PRS. However, further clinical studies are needed to confirm the effectiveness and safety of this therapeutic modality.
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