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Updated: Mar 20, 2026

Screening for Phytoestrogens using a Cell-based Estrogen Receptor β Reporter Assay
Published on: June 7, 2020
[EFFECTS OF DIFFERENT CLASSES OF PLANT HORMONES ON MAMMALIAN CELLS]
Abstract:
Plant hormones are signal molecules of different chemical structure, secreted by plant cells and acting at low concentrations as regulators of plant growth and differentiation. Certain plant hormones are similar to animal hormones or can be produced by animal cells. A number of studies show that the effect of biologically active components of plant origin including plant/phytohormones is much wider than was previously thought, but so far there are no objective criteria for assessing the influence of phytohormones on the physiological state of animal cells. Presented in the survey data show that plant hormones, which have different effects on plant growth and development (jasmonic, abscisic and gibberellic acids), are not neutral to the cells of animal origin, and animal cells response to them may be either positive or negative.
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