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Updated: Jul 17, 2026

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
Published on: April 12, 2019
Aggressive osteoblastoma. A case previously reported as a recurrent osteoid osteoma
K S Morton1, N F Quenville, C P Beauchamp
1Vancouver General Hospital, British Columbia, Canada.
Abstract:
We review the case of a 58-year-old man with a benign osteoblastic lesion. This originated in the base of the right second metacarpal and eventually involved several adjacent bones, persisting for at least 27 years despite 11 operations. It was originally reported in the literature as a recurrent osteoid osteoma, but we believe it is more properly diagnosed as an aggressive osteoblastoma, since the histological pattern did not change over the years. The lesion has remained locally aggressive with no evidence of malignant characteristics.
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