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Sleep Disordered Breathing and Adverse Pregnancy Outcomes
Mary Ashley Cain1, Judette M Louis2
1Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of South Florida Morsani College of Medicine, 2 Tampa General Circle, 6th Floor, Tampa, FL 33606, USA.
Clinics in Laboratory Medicine
|May 29, 2016
Summary
Sleep disordered breathing (SDB) in women of reproductive age is difficult to diagnose during pregnancy due to overlapping symptoms. SDB during pregnancy is linked to serious maternal and fetal health risks.
Area of Science:
- Reproductive health
- Sleep medicine
- Cardiovascular health
Background:
- Sleep disordered breathing (SDB) affects 0.6%–15% of reproductive-aged women.
- SDB diagnosis in pregnancy is challenging due to symptom overlap with normal pregnancy findings.
- SDB causes oxidative stress, inflammation, and is linked to cardiovascular risks in nonpregnant individuals.
Purpose of the Study:
- To highlight the diagnostic challenges of SDB in pregnancy.
- To review the impact of SDB on maternal and fetal health.
- To emphasize the association between SDB and adverse pregnancy outcomes.
Main Methods:
- Literature review of SDB in reproductive-aged women and pregnancy.
- Analysis of symptom overlap and diagnostic difficulties.
- Examination of SDB's physiological effects (oxidative stress, inflammation).
Main Results:
- SDB presents diagnostic challenges in pregnancy.
- SDB is associated with increased risks of gestational diabetes, preeclampsia, and fetal growth abnormalities.
- Repetitive arousals, sleep fragmentation, and hypoxias in SDB contribute to adverse outcomes.
Conclusions:
- SDB is a significant concern during pregnancy with potential for serious complications.
- Early identification and management of SDB in pregnant women are crucial.
- Further research is needed to improve SDB diagnosis and treatment in pregnancy.
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