Optic surface changes in Intraocular lens scaffold: An ex vivo study.

Area of Science:

• Ophthalmology
• Biomaterials Science
• Surgical Techniques

Background:

• Cataract surgery often involves intraocular lens (IOL) implantation.
• The IOL scaffold technique is a method used in certain ophthalmic procedures.
• Potential complications, such as micro injuries to the IOL optic, require thorough investigation.

Purpose of the Study:

• To evaluate the occurrence and nature of micro injuries on the intraocular lens (IOL) optic surface when using the IOL scaffold technique.
• To assess these optic changes through an ex vivo experimental study.

Main Methods:

• An ex vivo experimental study was conducted using 12 caprine eyes with moderate lens changes.
• Twelve IOLs (six acrylic hydrophilic, six polymethyl methacrylate) were implanted using the simulated IOL scaffold technique.
• Explanted IOLs were examined using light microscopy, phase contrast microscopy, and scanning electron microscopy (SEM) for surface defects.

Main Results:

• Four out of 12 IOLs exhibited linear mark defects on the mid-peripheral optic surface.
• No significant changes in these defects were observed after 24 hours.
• Microscopic abrasions or scratches were absent on the central 4 mm of the anterior optic surface; control IOLs showed no changes.

Conclusions:

• The IOL scaffold technique can lead to microscopic surface alterations on the IOL optic, specifically as linear defects in the mid-periphery.
• Intraoperative fluid maintenance is suggested as a method to potentially decrease the incidence of these IOL optic micro injuries.