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Related Experiment Videos

[In Process Citation].

Carla Adriana Santos1, Jorge Fonseca, Elisabete Carolino

  • 1GENE - Enteral Feeding Team. Hospital Garcia de Orta. Almada, Portugal.. carla.adriana.santos@hotmail.com.

Nutricion Hospitalaria
|May 31, 2016
PubMed
Summary
This summary is machine-generated.

Serum copper levels in gastrostomy-fed patients are mostly normal at baseline. Home-prepared formula feeding helps normalize low copper levels over 12 weeks in patients receiving gastrostomy (GEP).

Keywords:
CobreGEPGastrostomíaNutrición enteral

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Area of Science:

  • Clinical Nutrition
  • Trace Elements
  • Gastroenterology

Background:

  • Copper (Cu) is an essential trace element with poorly understood dynamics in patients receiving gastrostomy (GEP).
  • Nutritional status, including serum copper, albumin, transferrin, and BMI, requires monitoring in patients with feeding tubes.

Purpose of the Study:

  • To evaluate the serum copper (Cu) evolution in patients undergoing gastrostomy (GEP).
  • To assess serum Cu levels from baseline up to 12 weeks post-GEP in patients fed with home-prepared formulas.

Main Methods:

  • Prospective observational study involving 146 patients (56 with head and neck cancers, 90 with neurological dysphagia).
  • Serum Cu, albumin, transferrin, and BMI were measured at GEP, 4 weeks, and 12 weeks post-procedure.
  • Patient data included age, gender, NRS 2002 score, and underlying disease.

Main Results:

  • Most patients (89%) had normal serum Cu at GEP; 11% had low levels.
  • After 12 weeks, 95% of patients had normal serum Cu levels.
  • Low albumin (25%), transferrin (32%), and BMI (32%) were observed at 12 weeks, indicating persistent nutritional challenges despite Cu normalization.

Conclusions:

  • The majority of patients present with normal serum copper at the time of gastrostomy.
  • Home-prepared formula feeding appears adequate for the progressive normalization of serum copper in patients with initially low levels.
  • While copper levels normalize, other nutritional markers like albumin and transferrin remain low in a significant portion of patients post-gastrostomy.