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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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[Pustular psoriasis].

P Weisenseel1, D Wilsmann-Theis2, C Kahl1

  • 1SCIderm Clinical Research and Dermatologikum, Hamburg, Deutschland.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|June 1, 2016
PubMed
Summary
This summary is machine-generated.

Pustular skin diseases often resemble psoriasis, causing classification debates and varied terminology. This review details their epidemiology, clinical presentation, pathogenesis, genetics, and treatment options.

Keywords:
EpidemiologyGeneticsImpetigo herpetiformisPathogenesisTreatment

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Area of Science:

  • Dermatology
  • Immunology

Background:

  • Pustular skin diseases share similarities with plaque psoriasis, leading to classification controversies.
  • These conditions include generalized pustular psoriasis, acrodermatitis continua suppurativa, and palmoplantar pustular psoriasis.

Purpose of the Study:

  • To review the epidemiology, clinical features, pathogenesis, genetics, and therapy of various pustular skin diseases.
  • To clarify the classification and nomenclature of these debated dermatological conditions.

Main Methods:

  • Literature review of epidemiological, clinical, pathogenetic, genetic, and therapeutic data.
  • Synthesis of information on generalized pustular psoriasis, acrodermatitis continua suppurativa, acute pustulosis palmopantaris, palmoplantar pustular psoriasis, and TNF-blocker related psoriasiform dermatitis.

Main Results:

  • Pustular skin diseases present diverse clinical and pathogenetic profiles.
  • Classification remains challenging, with ongoing debate regarding their relationship to psoriasis.

Conclusions:

  • A comprehensive understanding of these conditions is crucial for accurate diagnosis and effective management.
  • Further research is needed to resolve classification ambiguities and optimize therapeutic strategies for pustular skin diseases.