Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dissociative states and epilepsy.

O Devinsky1, F Putnam, J Grafman

  • 1Division of Intramural Research, National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, MD.

Neurology
|June 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the brain basis of self-monitoring.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same author

Effects of ganaxolone on non-seizure outcomes in CDKL5 Deficiency Disorder: Double-blind placebo-controlled randomized trial.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society·2024
Same author

Potential of cannabinoids as treatments for autism spectrum disorders.

Journal of psychiatric research·2021
Same author

Clinical and MRI Predictors of Conversion From Mild Behavioural Impairment to Dementia.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry·2020
Same author

Neural correlates of unstructured motor behaviors.

Journal of neural engineering·2019
Same author

3T MRI Whole-Brain Microscopy Discrimination of Subcortical Anatomy, Part 2: Basal Forebrain.

AJNR. American journal of neuroradiology·2019
Same journal

Spatiotemporal Associations Between Cortical Microinfarcts and Cortical Superficial Siderosis in Cerebral Amyloid Angiopathy.

Neurology·2026
Same journal

Blood-Brain Barrier Disruption Before Interhospital Transfer for Thrombectomy and Clinical Outcome.

Neurology·2026
Same journal

At Death's Door: Cytosolic Dopamine in Patients With Parkinson Disease.

Neurology·2026
Same journal

Cerebral Artery Pulsatility, Premorbid Blood Pressure, and Small Vessel Disease on Brain Imaging: A Population-Based Study.

Neurology·2026
Same journal

Genetic Risk for Alzheimer Disease, Midlife Hypertension, and Dementia: The ARIC Neurocognitive Study.

Neurology·2026
Same journal

What is the Relevance of Neuron-Tumor Interactions in Malignant CNS Tumors?

Neurology·2026
See all related articles

This study found no direct link between epilepsy and dissociative disorders like multiple personality disorder (MPD). While some epilepsy patients showed dissociative symptoms, they were less severe than in MPD patients.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Clinical Psychology

Background:

  • Dissociative symptoms, including those seen in multiple personality disorder (MPD), can overlap with symptoms of seizure disorders.
  • The potential relationship between dissociative states and epilepsy requires further investigation to differentiate underlying mechanisms.

Observation:

  • Six patients diagnosed with MPD, previously suspected of having epilepsy, underwent intensive video-EEG monitoring.
  • Dissociative symptoms were assessed in 71 epileptic patients using the Dissociative Experiences Scale and compared to controls.

Findings:

  • None of the 6 MPD patients exhibited epilepsy, despite prior diagnoses.
  • Epileptic patients, particularly those with complex partial seizures, reported higher dissociative symptoms than controls, but lower than MPD patients.

Related Experiment Videos

  • Patients with partial seizures and dominant hemisphere foci showed increased depersonalization compared to those with nondominant foci.
  • Implications:

    • Epilepsy is unlikely to be the primary cause of dissociative symptoms.
    • Distinguishing between epilepsy and dissociative disorders is crucial for accurate diagnosis and treatment.
    • Further research may clarify the neurobiological underpinnings of dissociative experiences.