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Updated: Mar 20, 2026

A Murine Model of Vertical Sleeve Gastrectomy
Published on: December 18, 2017
Do gallstones found before sleeve gastrectomy behave the same as those formed after surgery due to weight loss?
Alexandria Conley1, Moayad Tarboush1, Wuttiporn Manatsathit2
1Department of Surgery, St John Hospital and Medical Center, 29000 Little Mack Avenue, St Clair Shores, Detroit, MI 48081, USA.
Background:
Gallstone formation is prevalent in the bariatric population and after weight loss. We believe that gallstones found preoperatively behave differently and may not cause significant complications as those developing after weight loss. Thus, prophylactic cholecystectomy before or during sleeve gastrectomy (SG) may not be necessary.
Methods:
Patients undergoing SG from January 2011 to May 2012 were evaluated for the presence of gallstones and development of symptoms or need for cholecystectomy postoperatively.
Results:
Group 1 (n = 18) had gallstones preoperatively. Group 2 (n = 29) developed gallstones after weight loss. Both groups' demographics were similar. Symptomatic gallstones occurred in 1 patient (5.6%) in group 1 and in 9 patients (31.0%) in group 2 (P = .19). Percent excess body mass index loss (%EBL) was 58 ± 24% vs 70 ± 22% (P = .11) with a mean follow-up of 8.9 ± 6.2 and 14.7 ± 3.9 months for group 1 and group 2, respectively (P = .005).
Conclusions:
Asymptomatic gallstones found before SG tend to have less risk of becoming symptomatic than those formed after weight loss. There was no statistical significant difference because of small sample. Prophylactic cholecystectomy, however, may not be warranted in these patients.

