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Ameloblastic Fibrosarcoma Arising in the Maxilla
Rachael R Pillay1, Arthur Bilski2, Martin Batstone3
1Department of Maxillofacial Surgery, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia; Translational Research Institute - Diamantina Institute, The University of Queensland, Woolloongabba, Queensland, Australia.
Background:
Ameloblastic fibrosarcoma (AFS) is a rare odontogenic neoplasm of the jaw that usually arises de novo or through a malignant change in the mesenchymal component of a preexisting or recurrent benign fibroma. The majority of AFS cases reported in the literature arise in the mandible.
Case Report:
A 35-year-old male presented with an asymptomatic left maxillary mass that on imaging was found to be effacing most of his maxillary sinus. He underwent a left maxillectomy with free-flap reconstruction and adjuvant radiotherapy to the tumor bed.
Conclusion:
Wide local excision remains the treatment of choice for AFS, given the poor survival rates of patients with recurrent disease. However, long-term studies and follow-up are needed to elucidate the role of adjuvant therapies in the primary treatment of AFS.
