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Ameloblastic Fibrosarcoma Arising in the Maxilla
Rachael R Pillay1, Arthur Bilski2, Martin Batstone3
1Department of Maxillofacial Surgery, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia; Translational Research Institute - Diamantina Institute, The University of Queensland, Woolloongabba, Queensland, Australia.
Ochsner Journal
|June 16, 2016
Summary
Ameloblastic fibrosarcoma (AFS), a rare jaw tumor, typically affects the mandible. Surgical excision is the primary treatment, but further research is needed on adjuvant therapies for better outcomes.
Area of Science:
- Oral and Maxillofacial Surgery
- Oncology
- Pathology
Background:
- Ameloblastic fibrosarcoma (AFS) is a rare odontogenic neoplasm.
- It typically arises de novo or from malignant transformation of a fibroma.
- Most reported cases occur in the mandible.
Purpose of the Study:
- To present a case of ameloblastic fibrosarcoma in the maxilla.
- To discuss the management and treatment of this rare condition.
Main Methods:
- A 35-year-old male patient presented with an asymptomatic left maxillary mass.
- Imaging revealed the mass effacing the maxillary sinus.
- Treatment involved left maxillectomy with free-flap reconstruction and adjuvant radiotherapy.
Main Results:
- The patient underwent surgical resection and adjuvant radiotherapy.
- Wide local excision is considered the treatment of choice for AFS.
- Recurrent disease is associated with poor survival rates.
Conclusions:
- Wide local excision is the preferred treatment for ameloblastic fibrosarcoma.
- Long-term studies are necessary to determine the efficacy of adjuvant therapies in primary AFS treatment.
