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Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

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Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
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Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
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Updated: Mar 19, 2026

Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury
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FDG and Beyond.

Dirk De Ruysscher1,2, Karin Haustermans3, Daniela Thorwarth4

  • 1Radiation Oncology, University Hospitals Leuven/KU Leuven, Louvain, Belgium. dirk.deruysscher@maastro.nl.

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer
|June 20, 2016
PubMed
Summary
This summary is machine-generated.

Fluorodeoxyglucose (FDG) remains the primary PET tracer in oncology. Advances in glucose metabolism molecular biology highlight FDG

Keywords:
FDGHypoxiaMolecular imagingPETTarget volumeTracer

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Area of Science:

  • Oncology
  • Nuclear Medicine
  • Molecular Biology

Background:

  • Fluorodeoxyglucose (FDG) is the most prevalent positron emission tomography (PET) tracer in clinical oncology.
  • The molecular biology of glucose metabolism has seen significant advancements, increasing the relevance of FDG.
  • Other PET tracers are gaining importance and will be briefly discussed.

Purpose of the Study:

  • To provide an in-depth discussion of FDG in clinical oncology.
  • To explore the significance of FDG in light of evolving glucose metabolism research.
  • To briefly introduce other relevant PET tracers.

Main Methods:

  • Review of current clinical oncology practices utilizing PET tracers.
  • Analysis of recent developments in the molecular biology of glucose metabolism.
  • Comparative overview of FDG and other emerging PET tracers.

Main Results:

  • FDG continues to be the most utilized PET tracer in oncology.
  • The molecular biology of glucose metabolism provides a crucial context for FDG's utility.
  • Emerging PET tracers show increasing importance.

Conclusions:

  • FDG remains a cornerstone PET tracer in oncology.
  • Understanding glucose metabolism advancements enhances the interpretation of FDG PET scans.
  • A broader range of PET tracers is becoming increasingly significant in oncological practice.