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Updated: Mar 19, 2026

Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station INBEST
Published on: April 23, 2015
PET-Based Personalized Management of Infectious and Inflammatory Disorders
Søren Hess1, Abass Alavi2, Sandip Basu3
1Department of Nuclear Medicine, Odense University Hospital, Sdr. Boulevard 29, Odense 5000, Denmark; Division of Nuclear Medicine, Department of Radiology and Nuclear Medicine, Hospital of South West Jutland, Finsensgade 10, Esbjerg 6700, Denmark; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Winsløwparken 19, 3, Odense 5000, Denmark.
Abstract:
It is challenging to diagnose and manage infectious and inflammatory diseases; symptoms are relatively nonspecific, the disease patterns are often systemic. Imaging is pivotal and fluorodeoxyglucose (FDG)-PET/computed tomography (CT) is increasingly used due to its high sensitivity whole-body approach. At present, the literature is still relatively sparse, but evidence for FDG-PET/CT is mounting in several domains, for example, detecting culprit lesions in systemic infections and inflammations, evaluation of disease extent and therapy monitoring, and many other domains have shown considerable potential, for example, atherosclerosis in systemic inflammation. We believe FDG-PET/CT is becoming a first-line modality for infections and inflammation.
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