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Updated: Mar 19, 2026

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection

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Published on: July 21, 2013

Treating Total Occlusions: Applying Force for Recanalization.

Aimee Sakes, Evelyn Regar, Jenny Dankelman

IEEE Reviews in Biomedical Engineering

|June 21, 2016

Summary

This summary is machine-generated.

This review analyzes endovascular devices for total occlusions, categorizing tools by force application. Optimizing force and design is key for successful chronic occlusion treatment.

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Area of Science:

Endovascular surgery
Biomedical engineering
Vascular medicine

Background:

Chronic and acute total occlusions pose significant challenges in vascular interventions.
Current endovascular treatment devices vary across coronary, peripheral, carotid, and intracranial arteries.

Purpose of the Study:

To review and analyze state-of-the-art endovascular devices for total occlusions.
To categorize devices based on the forces exerted during treatment.
To understand the working principles of these devices in relation to occlusion biomechanics.

Main Methods:

Comprehensive literature search in Scopus and Espacenet databases.
Review and categorization of 120 patents and 49 articles.
Classification of treatment tools into compression, resection, and conversion modalities.
Subdivision based on force direction (axial, radial, tangential) or energy conversion.

Main Results:

Identified treatment modalities include compression, resection, and conversion.
Force application is categorized by direction (axial, radial, tangential) or energy conversion.
Device working principles are strongly linked to occlusion and environmental biomechanical properties.

Conclusions:

Increasing procedural success, particularly in chronic occlusions, requires optimizing applied forces.
Buckling prevention methods can increase applied force.
Smart tip design and dynamic loading can decrease penetration force, while minimizing energy dissipation is crucial.