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Related Experiment Videos

[Pelvic lymph node dissection for invasive bladder cancer].

S Isaka, T Okano, N Sato

    Nihon Hinyokika Gakkai Zasshi. the Japanese Journal of Urology
    |March 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

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    Pelvic lymph node dissection during bladder cancer surgery revealed common iliac and external iliac nodes are most frequently involved. This procedure improved survival compared to historical controls without node dissection.

    Area of Science:

    • Urology
    • Oncology
    • Pathology

    Context:

    • Bladder cancer management involves radical cystectomy and urinary diversion.
    • Pelvic lymph node dissection (PLND) is a critical component of staging and treatment.
    • Understanding nodal involvement patterns is crucial for prognosis.

    Purpose:

    • To analyze the frequency and patterns of lymph node metastasis in bladder cancer patients undergoing radical cystectomy and PLND.
    • To correlate lymph node involvement with tumor grade and pathological stage.
    • To evaluate the survival outcomes in patients with and without nodal metastasis.

    Summary:

    • A study of 80 bladder cancer patients (1979-1988) undergoing radical cystectomy with PLND.
    • Common iliac and external iliac nodes showed the highest metastasis rates.

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  • Lymph node metastasis incidence increased with tumor grade and stage (P1: 3.7%, P2: 10%, P3: 17%).
  • Patients with nodal metastasis had poorer survival, but overall mean survival was longer than historical controls without node dissection.

    • Impact:

    • Highlights the significance of specific nodal groups (common iliac, external iliac) in bladder cancer metastasis.
    • Provides evidence for the prognostic value of lymph node status in bladder cancer.
    • Demonstrates improved survival outcomes with the inclusion of PLND in radical cystectomy for bladder cancer.