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Updated: Mar 19, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
"Exercise as medicine" in chronic kidney disease
T J Wilkinson1, N F Shur1, A C Smith1
1Leicester Exercise Kidney Team, John Wells Renal Unit, University Hospitals of Leicester NHS Trust and Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK.
Exercise is a powerful tool for managing chronic kidney disease (CKD) across all stages. This review highlights how prescribing physical activity can improve patient outcomes and overall health.
Area of Science:
- Nephrology
- Sports Medicine
- Preventive Medicine
Background:
- Exercise is recognized as 'exercise as medicine' for conditions like arthritis and diabetes.
- Exercise offers benefits such as reduced cardiovascular risk, inflammation, and improved physical function.
- Chronic kidney disease (CKD), affecting 10% of the population, is underutilized for exercise-based therapy.
Purpose of the Study:
- To review the significant role of exercise in managing chronic kidney disease (CKD).
- To provide guidance on the optimal administration and prescription of exercise for CKD patients.
Main Methods:
- Literature review summarizing current evidence on exercise and CKD.
- Analysis of exercise benefits across different stages of kidney disease (pre-dialysis, dialysis, transplant).
Main Results:
- Exercise demonstrates potential benefits for patients with varying severities of CKD.
- Physical activity can improve cardiovascular health, inflammation, and physical capacity in CKD patients.
Conclusions:
- Exercise should be considered a key component in the clinical management of CKD.
- Tailored exercise prescriptions are crucial for maximizing benefits in kidney disease patients.
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