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Updated: Mar 19, 2026

Fabricating Highly Open Porous Microspheres HOPMs via Microfluidic Technology
Published on: May 16, 2022
Modification of PDMS to fabricate PLGA microparticles by a double emulsion method in a single microfluidic device
Leila Montazeri1, Shahin Bonakdar2, Mojtaba Taghipour3
1Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran. Baharvand@Royaninstitute.org and Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran.
Abstract:
We present an easy, durable method to generate a partially hydrophilic/hydrophobic poly(dimethylsiloxane) (PDMS) microfluidic device. The functionality of this device was assessed in a double flow focusing design to fabricate core-shell structured poly(lactic-co-glycolic acid) (PLGA) microparticles (MPs).

