[Localized bullous pemphigoid triggered by erysipelas]

Area of Science:

• Dermatology
• Immunodermatology

Background:

• Bullous pemphigoid (BP) is an autoimmune blistering disease.
• Localized bullous pemphigoid is a rare variant with limited skin involvement.

Observation:

• A 63-year-old male presented with tense bullae on his left calf.
• The affected area was erythematous and followed two episodes of erysipelas.

Findings:

• Histological examination and direct immunofluorescence confirmed localized bullous pemphigoid.
• Erysipelas was identified as the likely provoking factor.

Implications:

• This case underscores the importance of recognizing localized bullous pemphigoid as a differential diagnosis.
• Awareness can prevent misdiagnosis and unnecessary antibiotic use, guiding towards appropriate therapies like topical steroids.