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Published on: December 30, 2025
Exercise manual for liver disease patients.
Vivian Limongi1, Daniele Costa Dos Santos1, Aurea Maria de Oliveira da Silva1
1Vivian Limongi, Daniele Costa dos Santos, Aurea Maria de Oliveira da Silva, Ilka de Fátima Santana Ferreira Boin, Raquel Silveira Bello Stucchi, Unit of Liver Transplantation, Hospital de Clinicas, State University of Campinas (Unicamp), Campinas 13020-060, Brazil.
This study shows that inspiratory muscle training significantly improves inspiratory muscle strength and functional capacity in liver transplant candidates. These improvements lead to a better quality of life for patients with liver disease.
Area of Science:
- Pulmonology and Gastroenterology
- Rehabilitation Medicine
- Transplant Surgery
Background:
- Liver transplantation candidates often experience reduced respiratory muscle strength and impaired quality of life.
- Ascites, a common complication in liver disease, can further exacerbate respiratory dysfunction.
Purpose of the Study:
- To evaluate the effectiveness of a home-based inspiratory muscle training program.
- To enhance inspiratory muscle strength and improve the quality of life in patients awaiting liver transplantation.
Main Methods:
- A 3-month randomized controlled trial involving liver transplant candidates.
- Intervention group performed daily home-based inspiratory muscle exercises with remote monthly supervision.
- Evaluated maximal inspiratory pressure (MIP), spirometry, muscle electrical activity (RMS), and quality of life (SF-36).
Main Results:
- Significant improvements in MIP were observed within both groups, but not between them.
- The intervention group showed significantly lower RMS of the diaphragm and higher functional capacity compared to the control group.
- Both groups reported improvements in general and mental health domains; however, ascites presence correlated with lower social functioning scores in the intervention group.
Conclusions:
- Home-based inspiratory muscle training effectively increases inspiratory muscle strength and functional capacity.
- These improvements contribute to an enhanced quality of life for individuals with liver disease.
- The findings support the integration of inspiratory muscle training into pre-transplant care protocols.
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