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Expression strategies for structural studies of eukaryotic membrane proteins

Joseph A Lyons1, Azadeh Shahsavar2, Peter Aasted Paulsen3

  • 1Danish Research Institute of Translational Neuroscience (DANDRITE), Nordic EMBL Partnership for Molecular Medicine, Aarhus University, Aarhus, Denmark; Centre for Membrane Pumps in Cells and Disease-PUMPkin, Danish National Research Foundation, Aarhus, Denmark; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.

Current Opinion in Structural Biology
|July 1, 2016
PubMed
Summary

Researchers are improving methods for determining the structures of eukaryotic membrane proteins, which are vital for cellular functions. Advances in expression systems and protein modification are increasing the availability of these crucial protein structures.

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