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Tuberculosis in Older Adults.
1Los Angeles County Department of Public Health, 123 West Manchester Boulevard, Inglewood, CA 90301, USA; Charles R. Drew University of Medicine and Science, Los Angeles, CA, USA.
Clinics in Geriatric Medicine
|July 10, 2016
Summary
Tuberculosis (TB) in older adults presents unique challenges due to atypical symptoms and difficult diagnosis. This review covers epidemiology, diagnosis, and management of TB in the elderly to improve prevention strategies.
Area of Science:
- Gerontology
- Infectious Diseases
- Public Health
Background:
- Tuberculosis (TB) is a leading infectious cause of death globally.
- Preventing and controlling TB in elderly populations is a significant public health challenge.
- Clinical presentations of TB in older adults can be atypical, mimicking age-related conditions.
Purpose of the Study:
- To review the epidemiology, pathogenesis, clinical characteristics, diagnosis, management, and prevention of Mycobacterium tuberculosis infection in aging adults.
- To highlight the specific challenges associated with TB in the elderly population.
- To provide a comprehensive overview for healthcare professionals managing TB in older individuals.
Main Methods:
- Literature review of current global data on TB in the elderly.
- Analysis of pathogenesis and clinical manifestations specific to aging adults.
- Synthesis of diagnostic and management strategies, including adverse drug reactions.
Main Results:
- TB in the elderly often presents with non-specific symptoms, complicating early diagnosis.
- Older adults are at higher risk for adverse drug reactions during TB treatment.
- Management requires careful consideration of comorbidities and physiological changes associated with aging.
Conclusions:
- Effective TB control in aging populations necessitates tailored strategies addressing diagnostic complexities and treatment challenges.
- Further research is needed to optimize TB prevention and care for community-dwelling and institutionalized older adults.
- Early recognition and appropriate management are crucial to reduce TB morbidity and mortality in the elderly.
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