Related Experiment Video
Updated: Mar 18, 2026

Effect of Artificial Tear Formulations on the Metabolic Activity of Human Corneal Epithelial Cells after Exposure to Desiccation
Published on: May 2, 2020
Tear Break-up Time in High Altitude Areas
1Professor of Ophthalmology, Manipal College of Medical Sciences, P.O.Box No.341, Pokhara, Nepal.
High altitude environments can cause abnormal tear film, leading to eye discomfort. A study found 24% of individuals had abnormal Tear Break-up Time (TBUT), indicating ocular issues in these conditions.
Area of Science:
- Ophthalmology
- Environmental Medicine
Background:
- High altitude environments present unique challenges to ocular health.
- Low humidity, windy conditions, and high UV radiation contribute to tear film abnormalities.
Purpose of the Study:
- To investigate tear film abnormalities in individuals residing in high altitude areas.
- To correlate environmental factors with ocular discomfort and conditions like pterygium.
Main Methods:
- Tear Break-up Time (TBUT) was measured in 100 subjects in Ladakh.
- Subjects included both local populations and those relocated from plains.
Main Results:
- 24% of individuals exhibited an abnormal TBUT (< 5 seconds).
- Symptomatic individuals with abnormal TBUT reported irritation, foreign body sensation, pain, watering, and redness.
- Pterygium was observed in 12 individuals, and interpalpebral congestion in 4.
Conclusions:
- A significant percentage (24%) of the high-altitude population demonstrated abnormal tear film function.
- Environmental factors at high altitudes likely contribute to ocular discomfort and conditions such as pterygium.
- Ocular surface health requires attention in high-altitude regions due to prevalent environmental stressors.
More Related Videos
09:26In Situ Time-dependent Dielectric Breakdown in the Transmission Electron Microscope: A Possibility to Understand the Failure Mechanism in Microelectronic Devices
Published on: June 26, 2015
09:40Measurement and Analysis of Atomic Hydrogen and Diatomic Molecular AlO, C2, CN, and TiO Spectra Following Laser-induced Optical Breakdown
Published on: February 14, 2014
Related Concept Videos
Escape Velocities of Gases
Variation of Atmospheric Pressure
Assuming the air temperature is constant at a given altitude and that the ideal gas law of thermodynamics describes the atmosphere to a good approximation, one can find the variation of atmospheric pressure with height.
Let p(y) be the atmospheric pressure at...
Requirements for Human Life
Oxygen
Atmospheric air is only about 20 percent oxygen, but that oxygen is a key component of the chemical reactions that keep the body alive, including the reactions that produce ATP. Brain cells are susceptible to a lack of oxygen because they require a...
Ending Relationships
Influence of Earth's Curvature and Atmospheric Refraction on Leveling
Application of Linearization and Approximation