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Updated: Mar 17, 2026

Synthesis and Characterization of Placental Chondroitin Sulfate A plCSA-Targeting Lipid-Polymer Nanoparticles
Published on: September 18, 2018
Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery
Oommen P Varghese1, Jianping Liu2, Karthi Sundaram1
1Department of Chemistry, Ångström Laboratory, Uppsala University, SE-75121, Sweden. oommen.op@kemi.uu.se.
Abstract:
Glycosaminoglycan derived nanoparticles are a promising delivery system owing to their unique tumour targeting ability. Exploiting fluorescein for inducing amphiphilicity in these biopolymers provides inherent imaging and drug stabilization capabilities by π-π stacking interactions with aromatic antineoplastic agents. This offers a versatile and highly customizable nanocarrier with narrow size distribution and high drug loading efficiency (80%) with sustained drug release.
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