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STRUCTURAL HEART ANOMALIES (REVIEW)

N Osovska1, N Kuzminova1, M Ovcharuk1

  • 1National Pyrohov Memorial Medical University, Internal Medicine Department N1, Vinnitsa, Ukraine.

Georgian Medical News
|July 22, 2016
PubMed

Insights

Structural heart anomalies (SHA), often linked to connective tissue dysplasia syndrome, include mitral valve prolapse and abnormal left ventricle chords. Multiple abnormal chords may indicate left ventricular non-compaction, a serious hereditary condition.

Area of Science:

  • Cardiology
  • Genetics
  • Developmental Biology

Background:

  • Structural heart anomalies (SHA) are congenital cardiovascular abnormalities.
  • SHA are associated with connective tissue dysplasia syndrome (CTDS), a common autosomal-dominant disorder.
  • Common SHA include mitral valve prolapse and abnormal left ventricle chords.

Purpose of the Study:

  • To describe the characteristics and clinical significance of structural heart anomalies.
  • To highlight the prognostic implications of specific SHA, such as abnormal left ventricle chords.

Main Methods:

  • Review of existing literature on structural heart anomalies and connective tissue dysplasia syndrome.
  • Analysis of clinical significance based on severity and impact on intracardial hemodynamics.

Main Results:

  • Mitral valve prolapse and abnormal left ventricle chords are frequent SHA.
  • The clinical impact of SHA varies with severity and hemodynamic effects.
  • Multiple abnormal left ventricle chords are prognostically significant.

Conclusions:

  • Structural heart anomalies are diverse congenital conditions impacting cardiovascular health.
  • Abnormal left ventricle chords, particularly multiple instances, warrant attention due to potential links to serious hereditary diseases like left ventricular non-compaction.

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