Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neuron Structure01:30

Neuron Structure

20.9K
Neurons are the main type of cell in the nervous system that generate and transmit electrochemical signals. They primarily communicate with each other using neurotransmitters at specific junctions called synapses. Neurons come in many shapes that often relate to their function, but most share three main structures: an axon and dendrites that extend out from a cell body.
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to...
20.9K
Neuron Structure01:31

Neuron Structure

235.3K
Overview
235.3K
Organization of the Brain01:30

Organization of the Brain

3.2K
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
3.2K
Organization of the Nervous System01:13

Organization of the Nervous System

11.9K
The nervous system is one of the most complex systems in our body. It is organized into two main divisions: the central nervous system (CNS) and the peripheral nervous system (PNS).
The CNS, comprising the brain and spinal cord, houses billions of neurons. The brain is housed in the skull, while the spinal cord is linked to the brain through the foramen magnum of the occipital bone and is surrounded by the protective structure of the vertebral column. It is responsible for processing various...
11.9K
Neural Circuits01:25

Neural Circuits

3.1K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
3.1K
Cerebrum: Anatomical Overview II01:11

Cerebrum: Anatomical Overview II

5.8K
Each cerebral hemisphere can be divided into three main regions. The outermost region, the cerebral cortex, is a thin layer (2 to 4 millimeters thick) made up of gray matter, consisting of neuron cell bodies, dendrites, glial cells, and blood vessels. The middle region, or white matter, is primarily composed of myelinated nerve fibers organized into three types of large tracts: association fibers, commissures, and projection fibers. Association fibers connect different areas within the same...
5.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Structured sampling of molecularly classified mossy fiber inputs by cerebellar granule cells.

Frontiers in computational neuroscience·2026
Same author

RAEM: random-access electron microscopy for revisitable 3D imaging.

bioRxiv : the preprint server for biology·2026
Same author

Connectomic evidence that ordered activity drives neuromuscular network formation.

Nature neuroscience·2026
Same author

FEABAS: A Stitching and Alignment Tool for Serial EM Data.

bioRxiv : the preprint server for biology·2026
Same author

DRIFT-EM enables direct wafer retrieval of ultrathin serial sections for large-volume electron microscopy.

Cell reports methods·2026
Same author

Cortical similarity networks in the rat brain: Postnatal development and sensitivity to early life stress.

Network neuroscience (Cambridge, Mass.)·2026

Related Experiment Video

Updated: Mar 17, 2026

Biocytin Recovery and 3D Reconstructions of Filled Hippocampal CA2 Interneurons
11:21

Biocytin Recovery and 3D Reconstructions of Filled Hippocampal CA2 Interneurons

Published on: November 20, 2018

9.1K

From Cajal to Connectome and Beyond.

Larry W Swanson1, Jeff W Lichtman2

  • 1Department of Biological Sciences, University of Southern California, Los Angeles, California 90089;

Annual Review of Neuroscience
|July 22, 2016
PubMed
Summary

Understanding the brain

Area of Science:

  • Systems neuroscience
  • Neuroscience
  • Computational neuroscience

Background:

  • A structure-function model is essential for linking mind, brain, and behavior.
  • A complete connectome, mapping structural connections, is a foundational requirement.
  • Nervous system connections are analyzed at macro, meso, micro, and nanolevels.

Purpose of the Study:

  • To outline the historical progression of connectome analysis across different scales.
  • To highlight the current challenges in extracting structure-function insights from complex neuroscience data.

Main Methods:

  • Historical review of connectome research from macro to nano levels.
  • Analysis of the evolution of tools and techniques in neuroscience.
Keywords:
big datanervous systemnetwork analysisneural connections

More Related Videos

Visualization of Cortical Modules in Flattened Mammalian Cortices
08:49

Visualization of Cortical Modules in Flattened Mammalian Cortices

Published on: January 22, 2018

13.9K
Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

6.1K

Related Experiment Videos

Last Updated: Mar 17, 2026

Biocytin Recovery and 3D Reconstructions of Filled Hippocampal CA2 Interneurons
11:21

Biocytin Recovery and 3D Reconstructions of Filled Hippocampal CA2 Interneurons

Published on: November 20, 2018

9.1K
Visualization of Cortical Modules in Flattened Mammalian Cortices
08:49

Visualization of Cortical Modules in Flattened Mammalian Cortices

Published on: January 22, 2018

13.9K
Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

6.1K

Main Results:

  • Connectome analysis has evolved from macrolevel studies in ancient times to nanolevel investigations with electron microscopy.
  • Significant advancements in understanding neural organization have been driven by technological progress.

Conclusions:

  • The greatest challenge in systems neuroscience is deriving meaningful structure-function relationships from extensive datasets.
  • Future research must focus on advanced data analysis techniques to unlock the brain's organizational principles.