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Updated: Mar 17, 2026

Non-invasive Imaging of Leukocyte Homing and Migration in vivo

Non-invasive Imaging of Leukocyte Homing and Migration in vivo

Published on: December 5, 2010

Neuroimaging in Leukemia.

Seyed Ali Nabavizadeh¹, Joel Stein¹, Suyash Mohan¹

¹Department of Radiology, Division of Neuroradiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

Hematology/Oncology Clinics of North America

|July 23, 2016

Summary

This summary is machine-generated.

Acute leukemia patients face craniocerebral issues from the disease or its treatments. Imaging, particularly Magnetic Resonance Imaging (MRI), is crucial for monitoring these central nervous system complications.

Keywords:

CT Central nervous system Leukemia Leukostasis MRI Neuroimaging

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Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia

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Published on: September 18, 2013

Area of Science:

Hematology
Oncology
Radiology

Background:

Leukemias are cancers of blood cells characterized by uncontrolled proliferation.
Acute leukemia can lead to diverse craniocerebral complications.
These complications may stem from direct leukemic infiltration, cerebrovascular events, infections, or treatment side effects.

Purpose of the Study:

To highlight the critical role of neuroimaging in managing acute leukemia patients.
To discuss the utility of various imaging modalities in detecting and characterizing central nervous system (CNS) complications.

Main Methods:

Review of imaging techniques used in evaluating CNS complications in acute leukemia.
Comparison of Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) for initial assessment and detailed evaluation.

Main Results:

CT scans are effective for initial detection of cerebrovascular complications.
MRI offers superior versatility and is the preferred modality for comprehensive CNS evaluation in leukemia patients.

Conclusions:

Neuroimaging is essential for the management of acute leukemia.
MRI is the imaging modality of choice for evaluating central nervous system involvement and complications in patients with acute leukemia due to its comprehensive capabilities.