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Arsenic-Containing Phosphatidylcholines: A New Group of Arsenolipids Discovered in Herring Caviar
Sandra A Viczek1, Kenneth B Jensen1, Kevin A Francesconi1
1Institute of Chemistry: Analytical Chemistry NAWI Graz University of Graz Universitätsplatz 1 8010 Graz Austria.
Abstract:
A new group of arsenolipids based on cell-membrane phosphatidylcholines has been discovered in herring caviar (fish roe). A combination of HPLC with elemental and molecular mass spectrometry was used to identify five arsenic-containing phosphatidylcholines; the same technique applied to salmon caviar identified an arsenic-containing phosphatidylethanolamine. The arsenic group in these membrane lipids might impart particular properties to the molecules not displayed by their non-arsenic analogues. Additionally, the new compounds have human health implications according to recent results showing high cytotoxicity for some arsenolipids.
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