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Updated: Mar 16, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Swallowing function and chronic respiratory diseases: Systematic review
Ines Ghannouchi1, Renée Speyer2, Kenji Doma3
1Department of Physiology and Functional Exploration, Farhat HACHED University Hospital of Sousse, Tunisia; EA 3880 (Research Group on Ventilator Handicap), Rouen University, France.
Chronic respiratory diseases like COPD and OSA significantly increase the risk of oropharyngeal dysphagia (swallowing difficulties). Further research is needed due to limited studies and varied diagnostic methods.
Area of Science:
- Medicine
- Pulmonology
- Gastroenterology
Background:
- Breathing and swallowing coordination is vital to prevent aspiration.
- Chronic respiratory diseases can disrupt this coordination.
- Understanding this link is crucial for patient care.
Purpose of the Study:
- To systematically review the impact of chronic respiratory diseases on swallowing.
- To synthesize current evidence on the relationship between respiratory conditions and dysphagia.
Main Methods:
- Conducted a systematic literature review using PubMed and Embase databases.
- Included studies published up to March 2016.
- Focused on articles related to Obstructive Sleep Apnea (OSA) and Chronic Obstructive Pulmonary Diseases (COPD).
Main Results:
- Twenty-six studies met the inclusion criteria, focusing on OSA (11 studies) and COPD (15 studies).
- No studies on other chronic respiratory diseases were identified.
- Data suggests a link between these diseases and oropharyngeal dysphagia.
Conclusions:
- Chronic respiratory diseases are associated with a higher prevalence of oropharyngeal dysphagia.
- The current body of research is limited by small study numbers and methodological variations.
- Further research is recommended to clarify the relationship and improve diagnostic consistency.
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