Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Eukaryotic Evolution01:24

Eukaryotic Evolution

43.3K
The endosymbiont theory is the most widely accepted theory of eukaryotic evolution; however, its progression is still somewhat debated. According to the nucleus-first hypothesis, the ancestral prokaryote first evolved a membrane to enclose DNA and form the nucleus. Conversely, the mitochondria-first hypothesis suggests that the nucleus was formed after endosymbiosis of mitochondria.
Contrary to the endosymbiont theory, the eukaryote-first hypothesis proposes that the simpler prokaryotic and...
43.3K
Prokaryotic vs. Eukaryotic Cells01:28

Prokaryotic vs. Eukaryotic Cells

7.1K
Prokaryotic and eukaryotic cells represent two fundamental types of cellular organization, differing significantly in structure, complexity, and function. These distinctions underpin the biological diversity seen across domains of life.Prokaryotic Cell CharacteristicsProkaryotic cells, exemplified by bacteria and archaea, are structurally simple and lack membrane-bound organelles, including a nucleus. Their genetic material consists of a single, circular DNA molecule in the nucleoid region,...
7.1K
Diversity of Protists I01:15

Diversity of Protists I

2.0K
Excavata is a diverse group of protists that includes both chemoorganotrophic and phototrophic species, with some thriving in anaerobic environments. Among the key groups within Excavata are diplomonads and parabasalids, which are flagellated protists that lack mitochondria and chloroplasts. These microorganisms typically inhabit anoxic environments, such as the intestines of animals, where they exist either symbiotically or as parasites, relying on fermentation for energy production. Some...
2.0K
The Tree of Life - Bacteria, Archaea, Eukaryotes02:40

The Tree of Life - Bacteria, Archaea, Eukaryotes

41.2K
The “tree of life” describes the evolution of life and the evolutionary relationships between organisms. The root of the tree is the common ancestor to all life on Earth. All other species radiate from this point, much like the branches of a tree. The numerous tips of these branches on the tree of life represent every living, or extant, species. Extinct species, which are species that no longer exist, can be found towards the center of the tree. Currently, these organisms, both...
41.2K
Three-Domain System of Life01:21

Three-Domain System of Life

2.1K
Ribosomal RNA (rRNA) sequence analysis revealed three distinct groups of cells: eukaryotes, bacteria, and archaea. In 1978, Carl R. Woese proposed the concept of domains, a taxonomic level above kingdoms, to differentiate these groups. He suggested that archaea and bacteria, despite their similar appearance, represent separate domains. Domains differ in rRNA, membrane lipid structure, transfer RNA, and antibiotic sensitivity.In this classification, animals, plants, and fungi belong to the...
2.1K
Replication in Eukaryotes01:29

Replication in Eukaryotes

18.6K
In eukaryotic cells, DNA replication is highly conserved and tightly regulated. Multiple linear chromosomes must be duplicated with high fidelity before cell division, so there are many proteins that fulfill specialized roles in the replication process. Replication occurs in three phases: initiation, elongation, and termination, and ends with two complete sets of chromosomes in the nucleus.
Many Proteins Orchestrate Replication at the Origin
Eukaryotic replication follows many of the same...
18.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum: Influence of nanoscale topology on the bactericidal efficiency of black silicon surfaces (2017 Nanotechnology28 245301).

Nanotechnology·2026
Same author

Reflections in the Shadow of Death: Values, Relationships, and the Search for the Meaning in the End-of-Life Care.

Omega·2026
Same author

Paramyxoviruses in Bats in Poland-The First Detection.

Pathogens (Basel, Switzerland)·2026
Same author

Rabies Reemergence, Central Europe, 2022-2024.

Emerging infectious diseases·2026
Same author

Designing Scalable Mechano-Virucidal Nanostructured Acrylic Surfaces for Enhanced Viral Inactivation.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Eco-friendly non-isocyanate polyurethane and carboxymethyl cellulose composite films reinforced with sodium lignosulfonate for sustainable packaging applications.

International journal of biological macromolecules·2026

Related Experiment Video

Updated: Mar 16, 2026

An Oligonucleotide-based Tandem RNA Isolation Procedure to Recover Eukaryotic mRNA-Protein Complexes
09:45

An Oligonucleotide-based Tandem RNA Isolation Procedure to Recover Eukaryotic mRNA-Protein Complexes

Published on: August 18, 2018

11.7K

"Race for the Surface": Eukaryotic Cells Can Win.

Vy T H Pham1, Vi Khanh Truong1, Anna Orlowska2

  • 1School of Science, Swinburne University of Technology , P.O. Box 218, Hawthorn, Victoria 3122, Australia.

ACS Applied Materials & Interfaces
|August 6, 2016
PubMed
Summary

Precise nanotopology on black silicon (bSi) surfaces effectively prevents bacterial co-infections and promotes eukaryotic cell growth. This biocompatible material offers a promising solution for developing advanced antibacterial nanomaterials for medical implants.

Keywords:
bactericidal surfacescompetitive colonizationinflammatory responsemicrobial contaminationnanostructures

More Related Videos

Ordering Single Cells and Single Embryos in 3D Confinement: A New Device for High Content Screening
14:22

Ordering Single Cells and Single Embryos in 3D Confinement: A New Device for High Content Screening

Published on: September 18, 2016

9.1K
Visualization of Endoplasmic Reticulum Subdomains in Cultured Cells
16:43

Visualization of Endoplasmic Reticulum Subdomains in Cultured Cells

Published on: February 18, 2014

13.8K

Related Experiment Videos

Last Updated: Mar 16, 2026

An Oligonucleotide-based Tandem RNA Isolation Procedure to Recover Eukaryotic mRNA-Protein Complexes
09:45

An Oligonucleotide-based Tandem RNA Isolation Procedure to Recover Eukaryotic mRNA-Protein Complexes

Published on: August 18, 2018

11.7K
Ordering Single Cells and Single Embryos in 3D Confinement: A New Device for High Content Screening
14:22

Ordering Single Cells and Single Embryos in 3D Confinement: A New Device for High Content Screening

Published on: September 18, 2016

9.1K
Visualization of Endoplasmic Reticulum Subdomains in Cultured Cells
16:43

Visualization of Endoplasmic Reticulum Subdomains in Cultured Cells

Published on: February 18, 2014

13.8K

Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Infectious Disease Research

Background:

  • Managing infections from medical implants is a growing global health challenge.
  • Bacterial co-colonization on implant surfaces poses a significant risk.
  • Existing treatments for implant-associated infections have limitations.

Purpose of the Study:

  • To investigate the potential of precise nanotopology in controlling bacterial co-infections on implant surfaces.
  • To evaluate the biocompatibility and eukaryotic cell proliferation on nanotopological substrata.
  • To explore the development of novel antibacterial nanomaterials for bionic applications.

Main Methods:

  • Fabrication of a model black silicon (bSi) substratum with precise nanotopology.
  • Infection of the substratum with live Gram-negative (Pseudomonas aeruginosa) and Gram-positive (Staphylococcus aureus) bacteria.
  • Dynamic study using real-time sequential confocal imaging to observe eukaryotic cell attachment and filopodia development (COS-7 fibroblast cells).
  • Assessment of the substratum's biocompatibility and inflammatory response.

Main Results:

  • The bSi nanotopology effectively intervened in bacterial co-colonization.
  • Eukaryotic cells demonstrated favorable proliferation on the nanotopological surface.
  • The bSi substratum was biocompatible and did not trigger an inflammatory response.
  • Dynamic imaging revealed successful attachment and filopodia development of fibroblast cells.

Conclusions:

  • Precise nanotopology on bSi surfaces can prevent bacterial co-infections while promoting eukaryotic cell proliferation.
  • The developed nanotopological substratum is biocompatible and suitable for medical implant applications.
  • This research paves the way for advanced, responsive antibacterial nanomaterials for prosthetics and implants.