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Enteric fever in India: current scenario and future directions
S Divyashree1, L E B Nabarro2,3, B Veeraraghavan4
1Department of Infectious Disease, Christian Medical College, Vellore, India.
Tropical Medicine & International Health : TM & IH
|August 7, 2016
Summary
Enteric fever, particularly drug-resistant strains originating in India, poses a significant health challenge. Addressing its control requires understanding its current status and future directions in India.
Area of Science:
- * Infectious Diseases
- * Microbiology
- * Public Health
Background:
- * Enteric fever is a significant cause of illness and death globally, especially in tropical regions.
- * The Indian subcontinent faces a high burden of enteric fever, including multidrug-resistant strains.
- * The H58 multidrug-resistant clade, originating in India, has spread across Asia and Africa, causing unrecognised outbreaks.
Purpose of the Study:
- * To review the current situation of enteric fever in India.
- * To identify factors hindering enteric fever control in India.
- * To discuss future strategies for enteric fever management in India.
Main Methods:
- * Review of existing literature and epidemiological data on enteric fever in India.
- * Analysis of phylogenetic studies on multidrug-resistant strains.
- * Discussion of public health and policy factors relevant to disease control.
Main Results:
- * India is a primary hub for enteric fever, with a high prevalence of multidrug-resistant strains.
- * The H58 clade's origin and spread highlight the global impact of antimicrobial resistance originating from the region.
- * Factors impeding control include socioeconomic conditions, sanitation, and healthcare access.
Conclusions:
- * Enteric fever remains a critical public health issue in India, exacerbated by drug resistance.
- * Effective control requires a multi-faceted approach addressing transmission, resistance, and healthcare infrastructure.
- * Future strategies must integrate surveillance, diagnostics, treatment, and prevention tailored to India's context.
Keywords:
IndeIndiaazithromycinazithromycineazitromicinadrug resistanceentericentéricaentériqueparatifoideaparatyphoidparatyphoïderesistencia a medicamentosrésistance aux médicamentstifoideatyphoidtyphoïdeMore Related Videos
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