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Textile Processes for Engineering Tissues with Biomimetic Architectures and Properties.
Afsoon Fallahi1, Ali Khademhosseini2, Ali Tamayol3
1Biomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA; Department of Polymer Engineering and Color Technology, Amirkabir University of Technology (Tehran Polytechnic), 424 Hafez Avenue, P.O. Box 15875-4413, Tehran, Iran.
Tissue engineering utilizes advanced textile technologies to create biomimetic constructs from fibers containing cells and biological factors. This review highlights key innovations in fiber fabrication and construct engineering for tissue regeneration.
Area of Science:
- Biomaterials Science
- Tissue Engineering
- Textile Technology
Background:
- Tissue engineering seeks to regenerate tissues using cell-laden constructs.
- Biomimetic properties are crucial for functional tissue regeneration.
- Textile technologies offer novel approaches for creating complex tissue scaffolds.
Purpose of the Study:
- To review recent advancements in textile technologies for tissue engineering.
- To highlight innovations in fiber fabrication for biomimetic constructs.
- To discuss progress in engineering cellular constructs using textile methods.
Main Methods:
- Review of prominent research in fiber fabrication techniques.
- Analysis of methods for assembling fibers into engineered constructs.
- Synthesis of findings on biomimetic properties achieved through textile approaches.
Main Results:
- Significant progress has been made in creating cell-laden fibers.
- Novel fiber assembly techniques enable the formation of intricate 3D constructs.
- Engineered constructs exhibit promising biomimetic characteristics for tissue regeneration.
Conclusions:
- Textile technologies are rapidly advancing the field of tissue engineering.
- Innovations in fiber and construct engineering are key to developing functional tissue replacements.
- Further research in this interdisciplinary area holds great potential for regenerative medicine.
