Related Experiment Video
Updated: Mar 16, 2026
Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture
Published on: November 25, 2025
[PROPHYLAXIS OF COMPLICATIONS OF LAPAROSCOPIC CHOLECYSTECTOMY IN PATIENTS WITH THE ISCHEMIC HEART DISEASE]
Insights
Cardioprotection with Vasopro preparation and low intra-abdominal pressure during laparoscopic surgery for gallstones may reduce cardiovascular complications in patients with ischemic heart disease.
Area of Science:
- Cardiology
- Gastroenterology
- Surgical Innovation
Context:
- Chronic calculous cholecystitis often coexists with ischemic heart disease.
- Laparoscopic cholecystectomy is a common surgical approach.
- Managing cardiovascular risks in these patients is critical.
Purpose:
- To analyze the impact of cardioprotection and pneumoperitoneum on cardiovascular complications.
- To evaluate the effectiveness of Vasopro preparation in high-risk surgical patients.
- To compare outcomes under different intra-abdominal pressure regimens.
Summary:
- 56 patients with gallstones and heart disease underwent laparoscopic cholecystectomy.
- Patients received either Vasopro cardioprotection or no cardioprotection.
- Intra-abdominal pressure was maintained at 5-7.9 mm Hg or 8-10 mm Hg.
- Lower complication rates were observed with Vasopro and lower pressure (5-7.9 mm Hg).
Impact:
- Suggests a strategy to mitigate cardiovascular risks during laparoscopic cholecystectomy.
- Highlights the importance of tailored preoperative preparation and intraoperative management.
- Provides evidence for optimizing surgical conditions in patients with comorbid cardiac conditions.
Abstract:
Results of examination and surgical tratment of 56 patients, suffering chronic calculous cholecystitis with concomitant schemic heart disease, were analyzed. In all the patients a laparoscopic cholecystectomy was performed. Monitoring of cardiovascular compli- cations was estimated with the help of a Helter recording of EGG intraoperatively and in the early postoperative period. Depending on a kind of preoperative preparation done, the patients were divided on two groups: those, to whom cardioprotection using a Vasopro preparation was conducted, and those without cardioprotection. Depending on the intraoperative pneumoperitoneum regime used in every group two subgroups were delineated: in intraabdominal pressure 5-7.9 mm Hg and 8-10 mm Hg. In the patients, to whom cardioprotection was conducted and operative intervention in a carboxyperitoneum regime performed while intraabdominal pressure 5-7.9 mm Hg, a frequency of cardiovascular complications was lesser than in a control group.
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