[EARLY DETECTION OF PREECLAMPSIA]

The preeclampsia is one of the most serious complications in the second half of the pregnancy with a high risk of perinatal maternal and neonatal mortality. The study is aiming to determine which pregnant women have a higher risk of developing preeclampsia with a view to the subsequent antenatal care, on the base of the individual factors.

From prospectively followed pacients is collected information by a questionnaire and sonographic examination at 11-13 weeks of gestation/w.g./ + 6 days, at the point of biochemical screening implementation. Selected is a group of women with one fetus pregnancy, non-smokers, without chromosomal and structural anomalies of the fetus, excluding those taking prophylactic low-dose of aspirin. The Doppler examination was transabdominaly performed on the ascending branch of the A. Uterina at the level of OICC.Pusatility and resistance index /Pi and Ri/ are bilaterally evaluated and converted to MoM for the relevant age of gestation.

The information about the taken values of Pi, Ri, the presence of diastolic incisures and the development of preeclampsia /PE/ or pregnancy indused hypertension /PIH/ is analyzed at 205 pregnant women. Out of them high values of Pi have 9 pregnant women, who subsequently developed PE or PlH.

The measurement of Pi at 12-13 weeks of gestation and presence of diastolic incisures have prognostic importance for the development of PE in the later period of pregnancy. The values of Ri, taken at 12-13 weeks of gestation have not essential importance in the forecast of preeclamsia development.