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Updated: Mar 16, 2026

The Perinatal Asphyxiated Lamb Model: A Model for Newborn Resuscitation
Published on: August 15, 2018
Novel Approaches to Neonatal Resuscitation and the Impact on Birth Asphyxia
Arjan B Te Pas1, Kristina Sobotka2, Stuart B Hooper3
1Division of Neonatology, Department of Pediatrics, Leiden University Medical Centre, J6-S, PO Box 9600, Leiden 2300 RC, The Netherlands.
Abstract:
Historically, recommendations for neonatal resuscitation were largely based on dogma, but there is renewed interest in performing resuscitation studies at birth. The emphasis for resuscitation following birth asphyxia is administering effective ventilation, as adequate lung aeration leads not only to an increase in oxygenation but also increased pulmonary blood flow and heart rate. To aerate the lung, an initial sustained inflation can increase heart rate, oxygenation, and blood pressure recovery much faster when compared with standard ventilation. Hyperoxia should be avoided, and extra oxygen given to restore cardiac function and spontaneous breathing should be titrated based on oxygen saturations.

