Related Experiment Video
Updated: Mar 16, 2026
Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice
Published on: May 10, 2019
Using Bera To Detect Persistence of Auditory Injury In High Risk Infants
Insights
High-risk infants show persistent auditory pathway injuries, as evidenced by significantly delayed Brainstem Evoked Response Audiometry (BERA) latencies and reduced wave amplitudes compared to normal infants.
Area of Science:
- Pediatric Audiology
- Neuroscience
- Infant Hearing Screening
Background:
- Infant hearing impairment is a significant concern.
- Early identification and intervention are crucial for development.
- High-risk infants require specialized audiological monitoring.
Purpose of the Study:
- To evaluate the hearing status of high-risk infants using Brainstem Evoked Response Audiometry (BERA).
- To compare audiological findings between high-risk and normal infants.
- To identify potential long-term auditory pathway effects in high-risk infants.
Main Methods:
- A cross-sectional comparative study involving 127 infants (6-18 months old), with 87 classified as high-risk.
- Brainstem Evoked Response Audiometry (BERA) with monaural acoustic stimulation (Cz-M₁/M₂ Montage).
- Analysis of absolute and interpeak latencies, and wave amplitudes (I, III, V) at 70 dB stimulus, compared between groups using SPSS v14.0.
Main Results:
- No significant differences in mean age or sex between high-risk and control groups.
- High-risk infants exhibited significantly higher mean absolute and interpeak latencies in both ears.
- Mean amplitudes of waves I and V were significantly smaller in high-risk infants compared to controls.
Conclusions:
- Persistent auditory pathway injury is evident in high-risk infants.
- BERA can detect subtle auditory pathway dysfunction in infants.
- Findings highlight the need for continued audiological surveillance in high-risk infant populations.
Objective:
This cross-sectional comparative study tried to assess the hearing status of the high risk infants by Brainstem Evoked Response Audiometry (BERA) and compare with that of the normal infants.
Material & Methods:
BERA was done on 127 infants of 6 to 18 months age of which 87 were high risk. All were given monaural acoustic stimulation using Cz-M₁/M₂ Montage. Waves I, III and V were analysed for absolute & interpeak latencies (in ms) & also for amplitudes (in µv) & their ratio. All the parameters were compared at 70 dB stimulus at p < 0.05 significance. Results were analysed by Statistical Package for Social Sciences (SPSS) software, version 14.0.
Results:
There was no significant difference of mean age and sex between the two group. In the study froup, mean values of all the Absolute and Inter-Peak Latencies of both ears were significantly higher and mean Amplitudes of waves I and V of both ears were significantly smaller than that of the Control group.
Conclusion:
The study found evidence of persistent injury to the various parts of the auditory pathway even as the high risk infants grew up.
