Comparison of a new optical biometer using swept-source optical coherence tomography and a biometer using optical...

Area of Science:

• Ophthalmology
• Biomedical Optics
• Medical Device Technology

Background:

• Accurate biometry is crucial for refractive outcomes after cataract surgery.
• Comparing different optical technologies for ocular measurements is essential for clinical practice.
• Swept-source optical coherence tomography (SS-OCT) and optical low-coherence reflectometry (OLCR) are common biometry methods.

Purpose of the Study:

• To evaluate the agreement between the IOLMaster 700 (SS-OCT) and Lenstar LS 900 (OLCR) for ocular biometry.
• To assess the clinical significance of any observed differences in measurements.
• To determine the impact of measurement differences on intraocular lens (IOL) power calculations.

Main Methods:

• Prospective evaluation of 183 eyes using both IOLMaster 700 and Lenstar LS 900.
• Measurements included axial length (AL), keratometry (K), anterior chamber depth (ACD), lens thickness, and central corneal thickness (CCT).
• Statistical analyses included paired t-tests, Pearson correlation, and Bland-Altman plots; IOL power was calculated using standard formulas.

Main Results:

• Excellent agreement and correlation were found for AL between SS-OCT and OLCR (23.61 mm vs 23.60 mm).
• Statistically significant but clinically insignificant differences were noted for AL and ACD.
• No statistically significant differences were found for K, lens thickness, or CCT; IOL power calculations showed no significant difference between devices.

Conclusions:

• The IOLMaster 700 and Lenstar LS 900 demonstrate very good agreement for ocular biometry.
• Observed statistically significant differences are clinically insignificant and do not affect IOL power calculations.
• Both SS-OCT and OLCR devices are reliable for pre-operative cataract surgery measurements.