Related Experiment Video
Updated: Mar 16, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Crystal structures of organoplatinum complexes containing alkyl-eugenoxyacetate and p-chloro-aniline
Hai Le Thi Hong1, Diep Dao Thi Bich1, Ngan Nguyen Bich1
1Chemistry Department, Hanoi National University of Education, 136 - Xuan Thuy - Cau Giay, Hanoi, Vietnam.
Abstract:
In the title complexes, trans-di-chlorido-(4-chloro-aniline-κN){3-meth-oxy-4-meth-oxy-carbonyl-meth-oxy-1-[(2,3-η)-prop-2-en-1-yl]benzene}-platinum(II) 0.1-hydrate, [PtCl2(C6H6ClN)(C13H16O4)]·0.1H2O, (I), and trans-di-chlorido-(4-chloro-aniline-κN){4-eth-oxy-carbonyl-meth-oxy-3-meth-oxy-1-[(2,3-η)-prop-2-en-1-yl]benzene}-platinum(II), [PtCl2(C6H6ClN)(C14H18O4)], (II), the Pt(II) metal atom displays a slightly distorted square-planar coordination geometry defined by the aniline N atom, two chloride anions (trans-positioned) and one ethyl-enic double bond. The least-squares planes through the two aromatic ring systems make an angle of 47.3 (3)° for (I) and 38.6 (2)° for (II). Both structures show disorder for the PtCl2 fragment, in the case of (I) even further extended towards the CH2-CH=CH2 ligand. An intra-molecular C-H⋯Cl hydrogen bond occurs in (I). In the crystal packing of (I), which is dominated by N-H⋯O and C-H⋯Cl inter-actions, a partially occupied water mol-ecule is observed on a twofold rotation axis with a refined site occupancy of 0.10 (1). A C-H⋯π inter-action is also present. In (II), inversion dimers form chains along the b-axis direction by N-H⋯O hydrogen bonds.
Related Concept Videos
Stereoisomerism
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...
Properties of Organometallic Compounds
Crystal Field Theory - Tetrahedral and Square Planar Complexes
Crystal field theory (CFT) is applicable to molecules in geometries other than octahedral. In octahedral complexes, the lobes of the dx2−y2 and dz2 orbitals point directly at the ligands. For tetrahedral complexes, the d orbitals remain in place, but with only four ligands located between the axes. None of the orbitals points directly at the tetrahedral ligands. However, the dx2−y2 and dz2 orbitals (along the Cartesian axes) overlap with the ligands less than the dxy,...
Coordination Compounds and Nomenclature
Enolate Mechanism Conventions
Coordination Number and Geometry

